How to Diagnose Hypertensive Nephropathy?

• Hypertensive Nephropathy often occurs in people between 40~50 years old and with 5~10 years’ history of Hypertension. Urination frequency increases at night at early stage, and then proteinuria occurs. For some cases, temporary gross hematuria may also occur without obvious back pain because of broken blood capillary. Course of disease progresses slowly and a few parts develop into Kidney Failure, and most are mild damage and abnormal in routine urinalysis. So how to diagnose Hypertensive Nephropathy?

  Check up Hypertensive Nephropathy by physical examination:

  Persistent increase of Hypertension (≥ 20.0/13 Kpa, 150/100 mmHg); palpebral edema and/or edema of both lower limbs and cardiac enlargement etc.; Arteriosclerotic Retinopathy, Malignant Arteriolar Nephrosclerosis may be diagnosed based on striped and flamboyancy bleeding on eye ground.

  Auxiliary examination of Hypertensive Nephropathy:

  I Most patients have mild-to-moderate proteinuria, and 24h urine protein is often between 1.5~2.0 g; with few visible components (red blood cell, white blood cell and hyaline cast) under microscopic examination, and may accompany hematuria; serum uric acid increases in early stage as well as NAG enzyme and β2-MG; Creatinine Clearance Rate (CCR) decreases slowly and urea nitrogen and creatinine increase. The dysfunction of renal tubule will occur earlier than dysfunction of glomerulus.

  II There is often no abnormality of kidney under imaging examination, and kidneys will shrink with different extent during stage of Kidney Failure; the damage of kidney function occurs at the early stage under radioisotope renography;

  III Renal biopsy is necessary for patients who are difficult to be diagnosed clinically. Correct and timely diagnosis is important to treat Hypertensive Nephropathy.

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  Note: Kidney disease should be treated as soon as possible for enhancing the therapeutic effect and improving your life quality.
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• TAG: Hypertensive Nephropathy diagnosis

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