Many patients often feel confused and are afraid when they are suspected of suffering from Membranous Nephropathy. In order to rest assured, patients had better have a well known of the general diagnosis of Membranous Nephropathy before deciding to make a specific inspection in a hospital. Then what should patients know about the diagnosis of Membranous Nephropathy?
The onset of Membranous Nephropathy is insidious, and it often presents as typical Nephrotic Syndrome with hypertension, microscopic hematuria, gross hematuria(rare) or low proteinuria selectivity. The patient's condition can maintain for many years, and part of the patients with Membranous Nephropathy can recover naturally. Membranous Nephropathy can be diagnosed according to the clinical characteristics mentioned above, but it should be diagnosed finally through the renal biopsy.
The exact cause of Membranous Nephropathy is still unknown yet. Clinically, Membranous Nephropathy is divided into Primary Membranous Nephropathy and Secondary Membranous Nephropathy. The cause of the former is not clear, and the latter often attacks with some autoimmune diseases such as Systemic Lupus Erythematosus, Hepatitis B and Hepatitis C.
In patients with Membranous Nephropathy, nearly 2/3 of the patients belong to Primary Membranous Nephropathy, and the remainder belong to Secondary Membranous Nephropathy.
The laboratory examination items of Primary Membranous Nephropathy mainly are proteinuria, hypoalbuminemia, hyperlipidaemia and lipoiduria. In order to exclude the secondary cause, patients have to make a immunology detection for Lupus Nephritis and other Connective Tissue Diseases, hepatitis B virus, hepatitis C virus, Syphilis, tumor maker and others.
Primary Membranous Nephropathy should be distinguished from other pathological types of Nephrotic Syndrome and Secondary Membranous Nephropathy such as Systemic Lupus Erythematosus. Children Membranous Nephropathy should be highly suspected and exclude secondary glomerular diseases, especially Hepatitis B associated glomerulonephritis and Lupus Nephritis. Older patients with Membranous Nephropathy should be aware of tumors.
Secondary Membranous Nephropathy usually has the clinical characters of Primary Membranous Nephropathy. In addition to the clinical characteristics, it is difficult to distinguish Primary Membranous Nephropathy and Secondary Membranous Nephropathy. Therefore, the diagnosis of Membranous Nephropathy should be diagnosed with the assistance of the combination of clinical characters, laboratory inspections and treatment trials.
The above-mentioned are some introductions about the diagnosis of Membranous Nephropathy, aiming to help you have a well known of the diagnosis, and develop a relaxing mentality. Thus you can face the disease positively. .
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